Documents › Agency rules › 2026-05482
Justice Department, Drug Enforcement Administration
Ordering Schedule I and II Controlled Substances Using DEA Form 222; Technical Amendments
Published March 20, 2026. Takes effect March 20, 2026. printed at 91 FR 13498. amending 21 CFR 1305.
This changes how the strongest controlled drugs may be ordered.
What the Rule Says It Does
On September 30, 2019, the Drug Enforcement Administration (DEA) published the final rule, New Single-Sheet Format for U.S. Official Order Form for Schedule I and II Controlled Substances (DEA Form 222). The final rule implemented a new single sheet format for DEA Form 222 and provided for a two-year transition period to switch from the triplicate form. This technical amendment corrects certain regulations erroneously not amended in the final rule which creates ambiguities. The amendment clarifies that a DEA Form 222 Power of Attorney may only be executed or revoked by a registrant, a partner of the registrant, or an officer of a registrant corporate entity. It resolves ambiguity over who may sign a DEA Form 222 and removes the obsolete transition provision for the triplicate version of DEA Form 222. These are conforming revisions that do not make any substantive changes to the regulations.
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The Order It Names
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- The rule itself
Justice Department, Drug Enforcement Administration, “Ordering Schedule I and II Controlled Substances Using DEA Form 222; Technical Amendments,” 91 FR 13498 (March 20, 2026). Effective March 20, 2026.
https://www.federalregister.gov/documents/2026/03/20/2026-05482/ordering-schedule-i-and-ii-controlled-substances-using-dea-form-222-technical-amendments - This page
“Ordering Schedule I and II Controlled Substances Using DEA Form 222; Technical Amendments,” a final rule naming an order indexed here. Read the Mandate, https://readthemandate.org/rules/rule-2026-05482/ (retrieved August 26, 2026).
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How This Rule Is Quoted
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